Five Chemicals Alternatives Assessment Study
An “alternatives assessment” methodology developed by TURI was used to evaluate the technical, economic, and environmental, health and safety feasibility of alternatives to the five chemicals for selected uses: lead, formaldehyde, tetrachloroethylene, hexavalent chromium, Di(2-ethylhexyl)phathalate (DEHP).
FormaldehydeCAS No. 50-00-0 EC No. 200-001-8 Index No. 605-001-00-5
Lead, metalCAS No. 7439-92-1 EC No. 231-100-4 Index No.
TetrachloroethyleneCAS No. 127-18-4 EC No. 204-825-9 Index No. 602-028-00-4
Chromium hexavalentCAS No. 18540-29-9 EC No. Index No.
Di(2-ethylhexyl) phthalateCAS No. 117-81-7 EC No. 204-211-0 Index No. 607-317-00-9
Other type of alternative
Formaldehyde is a carcinogen cat. 1 according to IARC (R40). It is also a sensitizer: may cause sensitization by skin contact (R43). Because of these two important risks, formaldehyde is listed in the hazardous Substance Database according to SUBSPORT Screening Criteria (SDSC).
Formaldehyde is toxic by inhalation, in contact with skin and if swallowed (R23 /24/25)
Tetrachloroethylene is a carcinogen cat. 2A according to IARC (R40). It is also endocrine disruptor cat. 2 (EU EDC database), as listed in the Substance Database according to SUBSPORT Screening Criteria (SDSC).
The substance is toxic for acuatic organisms, may cause long term adverse effects in the aquatic environment (51/53)
Chromium hexavalent is very dangerous as carcinogen 1 according to IARC and are listed in the hazardous Substance Database according to SUBSPORT Screening Criteria (SDSC).
Di(2-ethylhexyl) phthalate is a 2B carcinogen (according to IARC), it is on the OSPAR list of substances of possible concern, and endocrine disruptor cat. 1 (according to EU EDC database).
Also it is toxic for reproduction: may impair fertility (R60) and may cause harm to the unborn child (R61).
It is listed in the hazardous Substance Database according to SUBSPORT Screening Criteria (SDSC).
Who provided the information
Type of information supplier
Toxic Use Reduction Institute, University of Lowell Massachusetts.
June, 2006.Type of publication and availability
Scientific study, freely available
Publication or last update: 16.05.2012